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RAS BiologyБиоорганическая химия Russian Journal of Bioorganic Chemistry

  • ISSN (Print) 0132-3423
  • ISSN (Online) 1998-2860

Discovery and Identification of Plant Regulatory Peptides

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PII
S19982860S0132342325050022-1
DOI
10.7868/S1998286025050022
Publication type
Review
Status
Published
Authors
A.Yu. Skripnikov
  • Affiliation: Lomonosov Moscow State University, Biological Faculty
E.E. Vorobeva
  • Affiliation: Lomonosov Moscow State University, Biological Faculty
M.E. Taliansky
  • Affiliation: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
N.O. Kalinina
  • Affiliation: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Volume/ Edition
Volume 51 / Issue number 5
Pages
743-757
Abstract
Plant regulatory peptides represent a novel class of signaling molecules that play a central role in the regulation of plant growth, development, and stress responses. Owing to their high biological activity at low concentrations, they are considered promising biostimulants for environmentally sustainable agriculture. This review summarizes key theoretical approaches and experimental methods used for the discovery and identification of these peptides, including mass spectrometry, bioinformatics, bioassays, and screening. An overview is provided of the major peptides identified to date – such as systemin, PSK, PSY, AtPep1, CLV3, TDIF, CEP, and CIF – along with the methods used for their isolation, chemical synthesis, and functional validation. Special attention is given to model systems based on cell cultures and seedlings, which are commonly employed to screen peptide activity, as well as to strategies for identifying their corresponding receptors. The review highlights the critical role of bioassays as a final and indispensable stage in peptide discovery pipelines, enabling the functional evaluation of both identified and putative peptides.
Keywords
пептиды растений масс-спектрометрия предполагаемые пептиды регуляторные пептиды анализ роста корней сигнальные пептиды
Date of publication
01.05.2025
Year of publication
2025
Number of purchasers
0
Views
6

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