- PII
- S0132342325010145-1
- DOI
- 10.31857/S0132342325010145
- Publication type
- Article
- Status
- Published
- Authors
- Volume/ Edition
- Volume 51 / Issue number 1
- Pages
- 153-159
- Abstract
- A pair of new fluorogenic dyes from the arylidene-imidazolones’ family, containing simultaneously three electron-donating groups in the arylidene fragment, has been obtained. The optical properties of the resulting compounds were studied. It was shown that they are characterized by a noticeable bathochromic shift of absorption and emission maxima, as well as a pronounced variation of the position of the emission maximum depending on the properties of the environment. Using the HeLa Kyoto and Huh 7.5 cell lines as an example, we demonstrated that (Z)-5-(3,5-bis(dimethylamino)-4-(ethylamino)benzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one can be used as a selective fluorogenic dye for fluorescent labeling of lipid droplets, which indicates the potential of this fluorogen for staining these organelles in other living systems.
- Keywords
- арилиден-имидазолоны флуорогенные красители липидные капли адипосомы флуоресцентное мечение
- Date of publication
- 09.11.2025
- Year of publication
- 2025
- Number of purchasers
- 0
- Views
- 43
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